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... > Amino Acids, Peptides, and Proteins > Proteins > Nerve Tissue Proteins > Neuropeptides > Hypothalamic Hormones > Pituitary Hormone Release Inhibiting Hormones > Somatostatin
... > Amino Acids, Peptides, and Proteins > Peptides > Neuropeptides > Hypothalamic Hormones > Pituitary Hormone Release Inhibiting Hormones > Somatostatin
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Hypothalamic Hormones > Pituitary Hormone Release Inhibiting Hormones > Somatostatin
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Hypothalamic Hormones > Pituitary Hormone Release Inhibiting Hormones > Somatostatin
... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Peptide Hormones > Pancreatic Hormones > Somatostatin
Amino Acids, Peptides, and Proteins > Peptides > Peptide Hormones > Pancreatic Hormones > Somatostatin

Preferred term

Somatostatin  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Cyclic Somatostatin
  • Somatostatin 14
  • Somatostatin-14
  • Somatostatin, Cyclic
  • Somatotropin Release Inhibiting Factor
  • Somatotropin Release-Inhibiting Factor
  • Somatotropin Release Inhibiting Hormone
  • Somatotropin Release-Inhibiting Hormone
  • SRIH-14

Scope note

  • A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.

History note

  • 99

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URI

http://www.yso.fi/onto/mesh/D013004

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