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Concept information

Preferred term

Sphingomyelin Phosphodiesterase  

Type

  • Topical Descriptor

Entry terms

  • Sphingomyelinase
  • Sphingomyelinase C
  • Sphingomyelin Cholinephosphohydrolase
  • Sphingomyelin Cleaving Enzyme

Note

  • /defic: consider also NIEMANN-PICK DISEASE

Scope note

  • An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.

History note

  • 91(75); was see under PHOSPHODIESTERASES 1975-90

In other languages

URI

http://www.yso.fi/onto/mesh/D013108

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