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... > Viruses > RNA Viruses > Retroviridae > Gammaretrovirus > Leukemia Virus, Murine > Spleen Focus-Forming Viruses
... > Viruses > Oncogenic Viruses > Retroviridae > Gammaretrovirus > Leukemia Virus, Murine > Spleen Focus-Forming Viruses

Preferred term

Spleen Focus-Forming Viruses  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • SFFV

Note

  • infection: coordinate IM with RETROVIRIDAE INFECTIONS (IM) + TUMOR VIRUS INFECTIONS (IM) + LEUKEMIA, EXPERIMENTAL (IM) or LEUKEMIA, ERYTHROBLASTIC, ACUTE (IM) (for spontaneous erythroleukemia)

Scope note

  • Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukemia (LEUKEMIA, ERYTHROBLASTIC, ACUTE), manifested by splenic foci, SPLENOMEGALY, and POLYCYTHEMIA. Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences.

History note

  • 91(86); was see under MOUSE LEUKEMIA VIRUSES 1986-90

In other languages

URI

http://www.yso.fi/onto/mesh/D013155

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