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Enzymes and Coenzymes > Enzymes > Transferases > Alkyl and Aryl Transferases > Farnesyl-Diphosphate Farnesyltransferase

Preferred term

Farnesyl-Diphosphate Farnesyltransferase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Farnesyldiphosphate Farnesyldiphosphate Farnesyltransferase
  • Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase
  • Farnesyltransferase, Farnesyldiphosphate-Farnesyldiphosphate
  • Farnesyl Transferase, FPP-FPP
  • FPP FPP Farnesyl Transferase
  • FPP-FPP Farnesyl Transferase
  • Presqualene Diphosphate Synthase
  • Presqualene-Diphosphate Synthase
  • Squalene Synthase
  • Squalene Synthetase
  • Synthase, Presqualene-Diphosphate
  • Synthase, Squalene
  • Synthetase, Squalene
  • Transferase, FPP-FPP Farnesyl

Scope note

  • The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.

History note

  • 2006(1975)

In other languages

URI

http://www.yso.fi/onto/mesh/D013186

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