Concept information
Preferred term
Steroid 11-beta-Hydroxylase
Type
-
Topical Descriptor
Broader concept
Entry terms
- 11 beta Hydroxylase
- 11 beta-Hydroxylase
- CYP 11B1
- CYP11B1
- Cytochrome P450 11B1
- Cytochrome P-450(11 beta)
- Cytochrome P 450 CYP11B1
- Cytochrome P-450 CYP11B1
- Steroid 11 beta Monooxygenase
- Steroid 11-beta-Monooxygenase
- Steroid 11 Hydroxylase
- Steroid 11-Hydroxylase
- Steroid-11-Hydroxylase
Scope note
- A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
History note
- 2003 (1978)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D013252
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}