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Concept information

Preferred term

Steroid 11-beta-Hydroxylase  

Type

  • Topical Descriptor

Entry terms

  • 11 beta Hydroxylase
  • 11 beta-Hydroxylase
  • CYP 11B1
  • CYP11B1
  • Cytochrome P450 11B1
  • Cytochrome P-450(11 beta)
  • Cytochrome P 450 CYP11B1
  • Cytochrome P-450 CYP11B1
  • Steroid 11 beta Monooxygenase
  • Steroid 11-beta-Monooxygenase
  • Steroid 11 Hydroxylase
  • Steroid 11-Hydroxylase
  • Steroid-11-Hydroxylase

Scope note

  • A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).

History note

  • 2003 (1978)

URI

http://www.yso.fi/onto/mesh/D013252

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