Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 17-alpha-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 17-alpha-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 17-alpha-Hydroxylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 17 > Steroid 17-alpha-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 17 > Steroid 17-alpha-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 17 > Steroid 17-alpha-Hydroxylase

Preferred term

Steroid 17-alpha-Hydroxylase  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • 17,20 Desmolase
  • 17,20-Desmolase
  • 17,20 Lyase
  • 17,20-Lyase
  • 17 alpha Hydroxylase
  • 17 alpha-Hydroxylase
  • 17 alpha Hydroxylase Cytochrome P 450
  • 17 alpha-Hydroxylase Cytochrome P-450
  • 17 alpha-Hydroxylase, Steroid
  • 17 alpha-Monooxygenase, Steroid
  • 17-Hydroxylase, Steroid
  • 17-Monooxygenase, Steroid
  • alpha-Monooxygenase, Steroid 17
  • CYP17
  • Cytochrome P-450(17 alpha)
  • Cytochrome P-450(17-alpha)
  • Cytochrome P450(17 alpha)
  • P450(c17)
  • Steroid 17 alpha Hydroxylase
  • Steroid 17 alpha-Hydroxylase
  • Steroid 17 alpha Monooxygenase
  • Steroid 17 alpha-Monooxygenase
  • Steroid 17 Hydroxylase
  • Steroid 17-Hydroxylase
  • Steroid-17-Hydroxylase
  • Steroid 17 Monooxygenase
  • Steroid 17-Monooxygenase

Scope note

  • A microsomal cytochrome P450 enzyme that catalyzes the 17-alpha-hydroxylation of progesterone or pregnenolone and subsequent cleavage of the residual two carbons at C17 in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP17 gene, generates precursors for glucocorticoid, androgen, and estrogen synthesis. Defects in CYP17 gene cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL) and abnormal sexual differentiation.

History note

  • 2003 (1978)

In other languages

URI

http://www.yso.fi/onto/mesh/D013254

Download this concept:

RDF/XML TURTLE JSON-LD Created 4/15/77, last modified 6/1/16