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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 21-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 21-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Steroid Hydroxylases > Steroid 21-Hydroxylase
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 21 > Steroid 21-Hydroxylase
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 21 > Steroid 21-Hydroxylase
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 21 > Steroid 21-Hydroxylase

Preferred term

Steroid 21-Hydroxylase  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • 21 Hydroxylase
  • 21-Hydroxylase
  • Cytochrome P 450 21 Hydroxylase
  • Cytochrome P-450 21-Hydroxylase
  • Cytochrome P 450 c21
  • Cytochrome P-450 c21
  • Cytochrome P-450(c-21)
  • Cytochrome P450c21
  • Cytochrome P 450 CYP21
  • Cytochrome P-450 CYP21
  • P-450 c21, Cytochrome
  • Progesterone 21 Hydroxylase
  • Progesterone 21-Hydroxylase
  • Steroid 21 Hydroxylase
  • Steroid-21-Hydroxylase
  • Steroid 21 Monooxygenase
  • Steroid 21-Monooxygenase

Scope note

  • An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).

History note

  • 2003 (1978)

In other languages

URI

http://www.yso.fi/onto/mesh/D013255

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