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... > Organic Chemicals > Hydrocarbons > Hydrocarbons, Cyclic > Hydrocarbons, Aromatic > Polycyclic Aromatic Hydrocarbons > Indenes > Sulindac
Polycyclic Compounds > Polycyclic Aromatic Hydrocarbons > Indenes > Sulindac

Preferred term

Sulindac  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Aclin
  • Apo Sulin
  • Apo-Sulin
  • Arthrobid
  • Clinoril
  • Copal
  • Kenalin
  • MK 231
  • MK-231
  • MK231
  • Novo Sundac
  • Novo-Sundac
  • Nu Sulindac
  • Nu-Sulindac
  • Sulindal

Scope note

  • A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.

History note

  • 90(79); was see under INDENES 1979-89

In other languages

URI

http://www.yso.fi/onto/mesh/D013467

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