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Organic Chemicals > Organophosphorus Compounds > Phosphoramides > Thiotepa
... > Inorganic Chemicals > Electrolytes > Ions > Anions > Phosphates > Phosphoramides > Thiotepa
... > Inorganic Chemicals > Phosphorus Compounds > Phosphorus Acids > Phosphoric Acids > Phosphates > Phosphoramides > Thiotepa
... > Inorganic Chemicals > Acids > Acids, Noncarboxylic > Phosphorus Acids > Phosphoric Acids > Phosphates > Phosphoramides > Thiotepa
... > Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Azirines > Aziridines > Triethylenephosphoramide > Thiotepa

Preferred term

Thiotepa  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Thiophosphamide
  • Thio Tepa
  • Thio-Tepa
  • Triethylenethiophosphoramide
  • Tris(1-aziridinyl)phosphine Sulfide

Scope note

  • A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).

History note

  • 92; was THIO-TEPA 1963-91; THIOTEPA was see THIO-TEPA 1977-91

In other languages

URI

http://www.yso.fi/onto/mesh/D013852

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