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Concept information

Preferred term

Tretinoin  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Acid, all-trans-Retinoic
  • Acid, Retinoic
  • Acid, trans-Retinoic
  • Acid, Vitamin A
  • all trans Retinoic Acid
  • all-trans-Retinoic Acid
  • Retinoic Acid
  • trans Retinoic Acid
  • trans-Retinoic Acid
  • Vitamin A Acid

Scope note

  • An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).

History note

  • 80(75); was see under VITAMIN A 1975-79

In other languages

URI

http://www.yso.fi/onto/mesh/D014212

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