Concept information
Preferred term
Tuftsin
Type
-
Topical Descriptor
Broader concept
Entry terms
- L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine
- L-Thr-L-Lys-L-Pro-L-Arg
- Taftsin
Scope note
- N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
History note
- 84(75); was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93
URI
http://www.yso.fi/onto/mesh/D014405
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