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Concept information

Preferred term

Tuftsin  

Type

  • Topical Descriptor

Entry terms

  • L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine
  • L-Thr-L-Lys-L-Pro-L-Arg
  • Taftsin

Scope note

  • N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear leukocytes and neutrophils in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.

History note

  • 84(75); was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93

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URI

http://www.yso.fi/onto/mesh/D014405

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