Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Tumor Necrosis Factor-alpha
Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Tumor Necrosis Factors > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Tumor Necrosis Factors > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Tumor Necrosis Factors > Tumor Necrosis Factor-alpha
Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Monokines > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Monokines > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Monokines > Tumor Necrosis Factor-alpha
Carbohydrates > Glycoconjugates > Glycoproteins > Tumor Necrosis Factor-alpha
Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Tumor Necrosis Factor-alpha

Preferred term

Tumor Necrosis Factor-alpha  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Cachectin
  • Cachectin Tumor Necrosis Factor
  • Cachectin-Tumor Necrosis Factor
  • TNF-alpha
  • TNFalpha
  • TNF Superfamily, Member 2
  • Tumor Necrosis Factor
  • Tumor Necrosis Factor Ligand Superfamily Member 2

Scope note

  • Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

History note

  • 2005(1988)

In other languages

URI

http://www.yso.fi/onto/mesh/D014409

Download this concept:

RDF/XML TURTLE JSON-LD Created 5/8/87, last modified 3/16/23