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... > Enzymes and Coenzymes > Enzymes > Lyases > Carbon-Carbon Lyases > Carboxy-Lyases > Uroporphyrinogen Decarboxylase

Preferred term

Uroporphyrinogen Decarboxylase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Carboxy-Lyase, Uroporphyrinogen
  • Decarboxylase, Uroporphyrinogen III
  • Uroporphyrinogen Carboxy Lyase
  • Uroporphyrinogen Carboxy-Lyase
  • Uroporphyrinogen III Decarboxylase

Note

  • /defic permitted but consider also PORPHYRIA CUTANEA TARDA and HEPATOERYTHROPOIETIC PORPHYRIA

Scope note

  • An enzyme that catalyzes the decarboxylation of UROPORPHYRINOGEN III to coproporphyrinogen III by the conversion of four acetate groups to four methyl groups. It is the fifth enzyme in the 8-enzyme biosynthetic pathway of HEME. Several forms of cutaneous PORPHYRIAS are results of this enzyme deficiency as in PORPHYRIA CUTANEA TARDA; and HEPATOERYTHROPOIETIC PORPHYRIA.

History note

  • 91(76); was see under CARBOXY-LYASES 1976-90

In other languages

URI

http://www.yso.fi/onto/mesh/D014575

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