Concept information
Preferred term
Uroporphyrinogen III Synthetase
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cosynthase
- Cosynthetase, Uroporphyrinogen III
- Isomerase, Uroporphyrinogen
- Synthase, Uroporphyrinogen-III
- Uroporphyrinogen III Cosynthetase
- Uroporphyrinogen III Synthase
- Uroporphyrinogen-III Synthase
- Uroporphyrinogen Isomerase
Scope note
- An enzyme that catalyzes the cyclization of hydroxymethylbilane to yield UROPORPHYRINOGEN III and water. It is the fourth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by UROS gene. Mutations of UROS gene result in CONGENITAL ERYTHROPOIETIC PORPHYRIA.
History note
- 2005 (1975)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D014576
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}