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Concept information

Preferred term

von Willebrand Factor  

Type

  • Topical Descriptor

Entry terms

  • Factor VIIIR Ag
  • Factor VIIIR-Ag
  • Factor VIII Related Antigen
  • Factor VIII-Related Antigen
  • Factor VIIIR RCo
  • Factor VIIIR-RCo
  • Ristocetin Cofactor
  • Ristocetin Willebrand Factor
  • Ristocetin-Willebrand Factor
  • von Willebrand Protein

Note

  • / defic = VON WILLEBRAND DISEASE or specific type of Von Willebrand Disease

Scope note

  • A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

History note

  • 86(76); was see under BLOOD COAGULATION FACTORS 1976-85; FACTOR VIII RELATED ANTIGEN, previously in the Supplementary Chemical File, was mapped to both FACTOR VIII & ANTIGENS 1977-89

In other languages

  • Finnish

  • von Willebrand-faktori
  • von Willebrand-tekijä
  • von Willebrandin faktori
  • von Willebrandin tekijä
  • von Willebrandt -tekijä
  • von Willebrandt-faktori
  • von Willebrandtin faktori
  • von Willebrandtin tekijä
  • VW-faktori
  • VW-tekijä
  • VWF
  • Swedish

  • Willebrand-faktorn

URI

http://www.yso.fi/onto/mesh/D014841

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