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Concept information

Preferred term

2-Acetylaminofluorene  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 2-AAF
  • 2 Acetamidofluorene
  • 2-Acetamidofluorene
  • 2 Fluorenylacetamide
  • 2-Fluorenylacetamide
  • AAF, Aminofluorene
  • Aminofluorene AAF
  • Fluoren 2 ylacetamide
  • Fluoren-2-ylacetamide
  • N 2 Fluorenylacetamide
  • N-2-Fluorenylacetamide
  • N Acetyl 2 Aminofluorene
  • N-Acetyl-2-Aminofluorene

Scope note

  • A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

History note

  • 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79

In other languages

URI

http://www.yso.fi/onto/mesh/D015073

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