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... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Nucleotidyltransferases > 2',5'-Oligoadenylate Synthetase

Preferred term

2',5'-Oligoadenylate Synthetase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • (2'-5')An Polymerase
  • 2-5A Synthetase
  • 2,5 Oligoadenylate Polymerase
  • 2',5' Oligoadenylate Polymerase
  • 2',5'-Oligoadenylate Polymerase
  • 2,5 Oligoadenylate Synthetase
  • 2',5'-Oligo(A) Polymerase
  • 2',5'-Oligo(A) Synthetase
  • ATP-(2'-5')oligo(A)adenylyltransferase
  • Oligoadenylate Polymerase, 2,5
  • Oligoadenylate Synthetase, 2,5
  • Polymerase, 2,5 Oligoadenylate
  • Polymerase, 2',5'-Oligoadenylate
  • Synthetase, 2,5 Oligoadenylate

Scope note

  • An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.

History note

  • 83

In other languages

URI

http://www.yso.fi/onto/mesh/D015088

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