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Nucleic Acids, Nucleotides, and Nucleosides > Nucleosides > Deoxyribonucleosides > Dideoxynucleosides
Carbohydrates > Glycosides > Nucleosides > Deoxyribonucleosides > Dideoxynucleosides

Preferred term

Dideoxynucleosides  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • ddNus

Note

  • antivirals & antimetabolites

Scope note

  • Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.

History note

  • 89

In other languages

URI

http://www.yso.fi/onto/mesh/D015224

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