Concept information
Preferred term
HLA-C Antigens
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigens, HLA C
- Antigens, HLA-C
- HLA-C
Scope note
- Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).
History note
- 89
In other languages
-
Finnish
-
HL-C-antigeeni
-
HLA-C
-
Swedish
URI
http://www.yso.fi/onto/mesh/D015236
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