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Concept information

Preferred term

Phorbol 12,13-Dibutyrate  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Phorbol 12,13 Dibutyrate
  • Phorbol-12,13-Dibutyrate

Scope note

  • A phorbol ester found in CROTON OIL which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems.

History note

  • 89

In other languages

URI

http://www.yso.fi/onto/mesh/D015240

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