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Concept information

Enzymes and Coenzymes > Enzymes > DNA Restriction-Modification Enzymes

Preferred term

DNA Restriction-Modification Enzymes  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • DNA Restriction Modification Enzyme
  • DNA Restriction-Modification Enzyme
  • DNA Restriction Modification Enzymes
  • Enzyme, DNA Restriction-Modification
  • Modification System, Restriction
  • Modification Systems, Restriction
  • Restriction-Modification Enzyme, DNA
  • Restriction Modification System
  • Restriction-Modification System
  • Restriction Modification Systems
  • Restriction-Modification Systems
  • System, Restriction Modification
  • System, Restriction-Modification
  • Systems, Restriction Modification
  • Systems, Restriction-Modification

Scope note

  • Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.

History note

  • 89

In other languages

URI

http://www.yso.fi/onto/mesh/D015280

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