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Preferred term

Transforming Growth Factors  

Type

  • Topical Descriptor

Entry terms

  • Factor, Transforming Growth
  • Growth Factor, Transforming
  • Transforming Growth Factor

Note

  • general or unspecified; prefer specifics

Scope note

  • Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.

History note

  • 89

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URI

http://www.yso.fi/onto/mesh/D015291

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