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Nucleic Acids, Nucleotides, and Nucleosides > Nucleic Acids > Nucleic Acid Probes > Oligonucleotide Probes
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Laboratory Chemicals > Molecular Probes > Nucleic Acid Probes > Oligonucleotide Probes
... > Chemical Actions and Uses > Pharmacologic Actions > Diagnostic Uses of Chemicals > Molecular Probes > Nucleic Acid Probes > Oligonucleotide Probes

Preferred term

Oligonucleotide Probes  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Oligonucleotide Probe
  • Probe, Oligonucleotide

Scope note

  • Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin.

History note

  • 89

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URI

http://www.yso.fi/onto/mesh/D015345

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