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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Histocompatibility Antigens Class I
Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Histocompatibility Antigens Class I
Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Histocompatibility Antigens Class I
Biological Factors > Antigens > Isoantigens > Histocompatibility Antigens > Histocompatibility Antigens Class I
Biological Factors > Antigens > Antigens, Surface > Histocompatibility Antigens > Histocompatibility Antigens Class I

Preferred term

Histocompatibility Antigens Class I  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Antigen, Class I
  • Antigens, Class I
  • Class I Antigen
  • Class I Antigens
  • Class I Histocompatibility Antigen
  • Class I Histocompatibility Antigens
  • Class I Major Histocompatibility Antigen
  • Class I Major Histocompatibility Antigens
  • Class I Major Histocompatibility Molecules
  • Class I MHC Protein
  • Class I MHC Proteins
  • I Antigen, Class
  • MHC Class I Molecule
  • MHC Class I Molecules
  • MHC I Molecules
  • MHC-I Molecules
  • MHC I Peptide
  • MHC-I Peptide
  • MHC I Peptides
  • MHC-I Peptides
  • Molecules, MHC-I
  • Peptide, MHC-I
  • Peptides, MHC-I

Note

  • human & animal

Scope note

  • Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.

History note

  • 89

In other languages

URI

http://www.yso.fi/onto/mesh/D015395

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