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... > Enzymes and Coenzymes > Enzymes > Transferases > Acyltransferases > Acetyltransferases > Chloramphenicol O-Acetyltransferase

Preferred term

Chloramphenicol O-Acetyltransferase  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Acetyltransferase, Chloramphenicol
  • CAT Enzyme
  • Chloramphenicol Acetyltransferase
  • Chloramphenicol Transacetylase
  • Enzyme, CAT
  • Transacetylase, Chloramphenicol

Scope note

  • An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.

History note

  • 1998(1989)

In other languages

URI

http://www.yso.fi/onto/mesh/D015500

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