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Concept information

Preferred term

Down-Regulation  

Type

  • Topical Descriptor

Entry terms

  • Downregulation
  • Down-Regulation (Physiology)

Scope note

  • A negative regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.

History note

  • 2002 (1990)

In other languages

URI

http://www.yso.fi/onto/mesh/D015536

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