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Biological Factors > Toxins, Biological > Mycotoxins > Cytochalasins > Cytochalasin D
... > Heterocyclic Compounds > Heterocyclic Compounds, Fused-Ring > Heterocyclic Compounds, 2-Ring > Indoles > Cytochalasins > Cytochalasin D

Preferred term

Cytochalasin D  

Type

  • Topical Descriptor

Broader concept

Scope note

  • A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.

History note

  • 90

In other languages

URI

http://www.yso.fi/onto/mesh/D015638

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