Concept information
Preferred term
Pentostatin
Type
-
Topical Descriptor
Broader concept
Entry terms
- CI 825
- CI-825
- CI825
- Co-Vidarabine
- Deoxycoformycin
- Nipent
- NSC 218321
- NSC-218321
- NSC218321
Scope note
- A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
History note
- 1997 (1990); for CO-VIDARABINE use PENTOSTATIN 1982-1997
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D015649
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