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Concept information

Preferred term

Pentostatin  

Type

  • Topical Descriptor

Entry terms

  • CI 825
  • CI-825
  • CI825
  • Co-Vidarabine
  • Deoxycoformycin
  • Nipent
  • NSC 218321
  • NSC-218321
  • NSC218321

Scope note

  • A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.

History note

  • 1997 (1990); for CO-VIDARABINE use PENTOSTATIN 1982-1997

In other languages

URI

http://www.yso.fi/onto/mesh/D015649

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