Concept information
Preferred term
Osteocalcin
Type
-
Topical Descriptor
Broader concept
Entry terms
- 4 Carboxyglutamic Protein, Bone
- 4-Carboxyglutamic Protein, Bone
- Bone 4-Carboxyglutamic Protein
- Bone gamma Carboxyglutamic Acid Protein
- Bone gamma-Carboxyglutamic Acid Protein
- Bone Gla Protein
- Calcium Binding Protein, Vitamin K Dependent
- Calcium-Binding Protein, Vitamin K-Dependent
- Gla Protein, Bone
- Protein, Bone 4-Carboxyglutamic
- Protein, Bone Gla
- Vitamin K Dependent Bone Protein
- Vitamin K-Dependent Bone Protein
Scope note
- Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX.
History note
- 90; GLA-PROTEIN was see OSTEOCACLIN 1990-96
In other languages
-
Finnish
-
GLA-proteiini
-
Swedish
URI
http://www.yso.fi/onto/mesh/D015675
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