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Concept information

Preferred term

Oncogene Protein p21(ras)  

Type

  • Topical Descriptor

Entry terms

  • p21 Transforming Viral Protein
  • p21 v Ha ras
  • p21 v-Ha-ras
  • p21(v-Ha-ras)
  • p21 v H ras
  • p21 v-H-ras
  • p21(v-H-ras)
  • p21 v Ki ras
  • p21 v-Ki-ras
  • p21(v-Ki-ras)
  • p21(v-K-ras)
  • p21 v ras
  • p21 v-ras
  • ras Oncogene p21 Product
  • ras Oncogene Product p21
  • ras Oncogene Protein p21
  • v-Ha-ras, p21
  • v-H-ras, p21
  • v-Ki-ras, p21
  • v-ras, p21

Note

  • coord with specific virus

Scope note

  • Transforming protein encoded by ras oncogenes. Point mutations in the cellular ras gene (c-ras) can also result in a mutant p21 protein that can transform mammalian cells. Oncogene protein p21(ras) has been directly implicated in human neoplasms, perhaps accounting for as much as 15-20% of all human tumors. This enzyme was formerly listed as EC 3.6.1.47.

History note

  • 1990

In other languages

URI

http://www.yso.fi/onto/mesh/D015689

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