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Concept information

Preferred term

Gene Products, nef  

Type

  • Topical Descriptor

Entry terms

  • 3' orf Protein
  • 3'-orf Protein
  • Gene Product, nef
  • nef Gene Product
  • nef Gene Products
  • nef Protein

Scope note

  • Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.

History note

  • 91(90); was see under VIRAL REGULATORY PROTEINS 1990

In other languages

URI

http://www.yso.fi/onto/mesh/D015693

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