Concept information
Preferred term
Gene Products, nef
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- 3' orf Protein
- 3'-orf Protein
- Gene Product, nef
- nef Gene Product
- nef Gene Products
- nef Protein
Scope note
- Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.
History note
- 91(90); was see under VIRAL REGULATORY PROTEINS 1990
In other languages
-
Finnish
-
nef-geenituote
-
Swedish
URI
http://www.yso.fi/onto/mesh/D015693
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