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Concept information

Preferred term

CD4 Antigens  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD4
  • Antigens, CD4
  • Antigens, T-Cell T4
  • CD4 Antigen
  • CD4 Molecule
  • CD4 Receptor
  • CD4 Receptors
  • CD4 Receptors, Surface
  • CD4 Receptor, Surface
  • Receptor, CD4
  • Receptors, CD4
  • Receptors, Surface CD4
  • Surface CD4 Receptor
  • Surface CD4 Receptors
  • T4 Antigens, T Cell
  • T4 Antigens, T-Cell
  • T-Cell T4 Antigens

Note

  • for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN

Scope note

  • 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.

History note

  • 2018 (1989); use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989

In other languages

URI

http://www.yso.fi/onto/mesh/D015704

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RDF/XML TURTLE JSON-LD Created 6/19/89, last modified 6/30/21