Concept information
Preferred term
CD4 Antigens
Type
-
Topical Descriptor
Entry terms
- Antigen, CD4
- Antigens, CD4
- Antigens, T-Cell T4
- CD4 Antigen
- CD4 Molecule
- CD4 Receptor
- CD4 Receptors
- CD4 Receptors, Surface
- CD4 Receptor, Surface
- Receptor, CD4
- Receptors, CD4
- Receptors, Surface CD4
- Surface CD4 Receptor
- Surface CD4 Receptors
- T4 Antigens, T Cell
- T4 Antigens, T-Cell
- T-Cell T4 Antigens
Note
- for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN
Scope note
- 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
History note
- 2018 (1989); use ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1989
In other languages
-
Finnish
-
CD4-antigeeni
-
Swedish
-
Antigener, CD4
-
CD4 molekyl
-
CD4 receptorer
URI
http://www.yso.fi/onto/mesh/D015704
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