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Hemic and Immune Systems > Immune System > Mononuclear Phagocyte System > Macrophages > Giant Cells, Langhans
Cells > Myeloid Cells > Macrophages > Giant Cells, Langhans
Hemic and Immune Systems > Immune System > Phagocytes > Macrophages > Giant Cells, Langhans
Cells > Phagocytes > Macrophages > Giant Cells, Langhans
Cells > Connective Tissue Cells > Macrophages > Giant Cells, Langhans
Cells > Giant Cells > Giant Cells, Langhans

Preferred term

Giant Cells, Langhans  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Cells, Langhans Giant
  • Cells, Langhans-Type Giant
  • Giant Cells, Langhans-Type
  • Langhans Giant Cells
  • Langhans Type Giant Cells
  • Langhans-Type Giant Cells

Note

  • do not confuse with LANGERHANS CELLS nor with ISLETS OF LANGERHANS

Scope note

  • Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity.

History note

  • 91(90); was see under GIANT CELLS 1990

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URI

http://www.yso.fi/onto/mesh/D015744

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