Concept information
Preferred term
Complement C3a
Type
-
Topical Descriptor
Broader concept
Entry terms
- C3a Complement
- Complement 3a
- Complement, C3a
- Complement Component 3a
- Component 3a, Complement
Scope note
- The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.
History note
- 2006 (1990)
In other languages
-
Finnish
-
C3a
-
Swedish
URI
http://www.yso.fi/onto/mesh/D015926
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