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Concept information

Preferred term

Complement C3a  

Type

  • Topical Descriptor

Entry terms

  • C3a Complement
  • Complement 3a
  • Complement, C3a
  • Complement Component 3a
  • Component 3a, Complement

Scope note

  • The smaller fragment generated from the cleavage of complement C3 by C3 CONVERTASE. C3a, a 77-amino acid peptide, is a mediator of local inflammatory process. It induces smooth MUSCLE CONTRACTION, and HISTAMINE RELEASE from MAST CELLS and LEUKOCYTES. C3a is considered an anaphylatoxin along with COMPLEMENT C4A; COMPLEMENT C5A; and COMPLEMENT C5A, DES-ARGININE.

History note

  • 2006 (1990)

In other languages

URI

http://www.yso.fi/onto/mesh/D015926

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