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Concept information

Preferred term

Complement C4b  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • C4b Complement
  • Complement 4b
  • Complement, C4b
  • Complement Component 4b
  • Component 4b, Complement

Scope note

  • The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).

History note

  • 2006 (1990)

In other languages

URI

http://www.yso.fi/onto/mesh/D015935

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