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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Complement System Proteins > Complement Membrane Attack Complex

Preferred term

Complement Membrane Attack Complex  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • C5b 8 poly C9
  • C5b-8-poly-C9
  • C 5b-9
  • C5b-9
  • Complement Complex C5b 9
  • Complement Complex C5b-9
  • Complement Complex, Terminal
  • Complex, Terminal Complement
  • Cytolytic Terminal Complement Complex
  • Membrane Attack Complex
  • Terminal Complement Complex

Scope note

  • A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC.

History note

  • 90

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URI

http://www.yso.fi/onto/mesh/D015938

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