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Concept information

Preferred term

Tumor Suppressor Protein p53  

Type

  • Topical Descriptor

Entry terms

  • Cellular Tumor Antigen p53
  • Oncoprotein p53
  • p53 Antigen
  • p53 Tumor Suppressor Protein
  • Phosphoprotein, pp53
  • pp53 Phosphoprotein
  • TP53 Protein
  • TRP53 Protein

Scope note

  • Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.

History note

  • 2005(1991);

In other languages

URI

http://www.yso.fi/onto/mesh/D016159

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