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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Retinoblastoma Protein
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Retinoblastoma Protein
Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins > Retinoblastoma Protein
Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > Retinoblastoma Protein

Preferred term

Retinoblastoma Protein  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Rb1 Gene Product
  • Rb Gene Product
  • Rb Protein

Note

  • /biosyn /drug eff /physiol /ultrastruct permitted

Scope note

  • Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.

History note

  • 91

In other languages

URI

http://www.yso.fi/onto/mesh/D016160

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RDF/XML TURTLE JSON-LD Created 6/19/90, last modified 6/30/05