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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > Receptors, Lymphocyte Homing > Lymphocyte Function-Associated Antigen-1
... > Biological Factors > Antigens > Antigens, Surface > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Cell Adhesion Molecules > CD11 Antigens > Lymphocyte Function-Associated Antigen-1
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Integrins > Receptors, Leukocyte-Adhesion > Lymphocyte Function-Associated Antigen-1

Preferred term

Lymphocyte Function-Associated Antigen-1  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • alphaLbeta2, Integrin
  • Integrin alphaLbeta2
  • Leukocyte Function Associated Antigen-1
  • LFA-1

Scope note

  • An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.

History note

  • 1991

In other languages

  • LFA-1-antigeeni

    Finnish

  • imusolujen toimintaan liittyvä antigeeni-1
  • integriini alfaLbeeta2
  • LFA-1
  • lymfosyyttien toimintaan liittyvä antigeeni-1

URI

http://www.yso.fi/onto/mesh/D016169

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