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Concept information

Preferred term

Macrophage Colony-Stimulating Factor  

Type

  • Topical Descriptor

Entry terms

  • Colony Stimulating Factor 1
  • Colony-Stimulating Factor 1
  • Colony Stimulating Factor, Macrophage
  • Colony-Stimulating Factor, Macrophage
  • CSF-1
  • CSF-M
  • M-CSF

Scope note

  • A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

History note

  • 91

In other languages

URI

http://www.yso.fi/onto/mesh/D016173

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