Concept information
...
Intercellular Signaling Peptides and Proteins
Cytokines
Hematopoietic Cell Growth Factors
Colony-Stimulating Factors
...
Intercellular Signaling Peptides and Proteins
Cytokines
Hematopoietic Cell Growth Factors
Colony-Stimulating Factors
Preferred term
Macrophage Colony-Stimulating Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Colony Stimulating Factor 1
- Colony-Stimulating Factor 1
- Colony Stimulating Factor, Macrophage
- Colony-Stimulating Factor, Macrophage
- CSF-1
- CSF-M
- M-CSF
Scope note
- A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
History note
- 91
In other languages
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Finnish
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M-CSF
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makrofaagikasvutekijä
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Swedish
URI
http://www.yso.fi/onto/mesh/D016173
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