Concept information
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Intercellular Signaling Peptides and Proteins
Cytokines
Hematopoietic Cell Growth Factors
Colony-Stimulating Factors
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Intercellular Signaling Peptides and Proteins
Cytokines
Hematopoietic Cell Growth Factors
Colony-Stimulating Factors
Preferred term
Granulocyte-Macrophage Colony-Stimulating Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cell-Stimulating Factor, Histamine-Producing
- Colony Stimulating Factor, Granulocyte Macrophage
- Colony-Stimulating Factor, Granulocyte-Macrophage
- CSF-2
- CSF-GM
- GM-CSF
- Histamine Producing Cell Stimulating Factor
- Histamine-Producing Cell-Stimulating Factor
- TC-GM-CSF
- Tumor Cell Human GM Colony Stimulating Factor
- Tumor-Cell Human GM Colony-Stimulating Factor
Scope note
- An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
History note
- 91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91
In other languages
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Finnish
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GM-CSF
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granulosyytti-makrofaagikasvutekijä
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Swedish
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GM-CSF
URI
http://www.yso.fi/onto/mesh/D016178
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