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Concept information

Preferred term

Granulocyte-Macrophage Colony-Stimulating Factor  

Type

  • Topical Descriptor

Entry terms

  • Cell-Stimulating Factor, Histamine-Producing
  • Colony Stimulating Factor, Granulocyte Macrophage
  • Colony-Stimulating Factor, Granulocyte-Macrophage
  • CSF-2
  • CSF-GM
  • GM-CSF
  • Histamine Producing Cell Stimulating Factor
  • Histamine-Producing Cell-Stimulating Factor
  • TC-GM-CSF
  • Tumor Cell Human GM Colony Stimulating Factor
  • Tumor-Cell Human GM Colony-Stimulating Factor

Scope note

  • An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.

History note

  • 91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91

In other languages

URI

http://www.yso.fi/onto/mesh/D016178

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RDF/XML TURTLE JSON-LD Created 6/19/90, last modified 3/16/23