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... > Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Hematopoietic Cell Growth Factors > Colony-Stimulating Factors > Granulocyte Colony-Stimulating Factor
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Hematopoietic Cell Growth Factors > Colony-Stimulating Factors > Granulocyte Colony-Stimulating Factor
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Hematopoietic Cell Growth Factors > Colony-Stimulating Factors > Granulocyte Colony-Stimulating Factor
Carbohydrates > Glycoconjugates > Glycoproteins > Colony-Stimulating Factors > Granulocyte Colony-Stimulating Factor
Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Colony-Stimulating Factors > Granulocyte Colony-Stimulating Factor

Preferred term

Granulocyte Colony-Stimulating Factor  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • Colony Stimulating Factor, Granulocyte
  • Colony-Stimulating Factor, Granulocyte
  • Factor, Myeloid Growth
  • G-CSF
  • Growth Factor, Myeloid
  • Myeloid Growth Factor

Scope note

  • A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.

History note

  • 91

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URI

http://www.yso.fi/onto/mesh/D016179

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