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Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Dystrophin
Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Dystrophin
Amino Acids, Peptides, and Proteins > Proteins > Contractile Proteins > Muscle Proteins > Dystrophin

Preferred term

Dystrophin  

Type

  • Topical Descriptor

Broader concept

Related concepts

Note

  • a muscle protein: see MeSH definition for relation to musc dystrophy; /biosyn /drug eff /physiol /ultrastruct permitted

Scope note

  • A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack dystrophin completely while those with Becker muscular dystrophy have dystrophin of an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN and alpha-actinin but the precise function of dystrophin is not clear. One possible role might be to preserve the integrity and alignment of the plasma membrane to the myofibrils during muscle contraction and relaxation. MW 400 kDa.

History note

  • 91

In other languages

URI

http://www.yso.fi/onto/mesh/D016189

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