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Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Cyclin-Dependent Kinases > Maturation-Promoting Factor
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Maturation-Promoting Factor
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Maturation-Promoting Factor
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Proline-Directed Protein Kinases > Cyclin-Dependent Kinases > Maturation-Promoting Factor

Preferred term

Maturation-Promoting Factor  

Type

  • Topical Descriptor

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Entry terms

  • Histone H1 Kinase, Growth Associated
  • Histone H1 Kinase, Growth-Associated
  • Histone H1 Kinase, M Phase Specific
  • Histone H1 Kinase, M-Phase-Specific
  • Mitosis Promoting Factor
  • Mitosis-Promoting Factor
  • M Phase Promoting Factor
  • M Phase-Promoting Factor

Scope note

  • Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.

History note

  • 91; HISTONE H1 KINASE, M-PHASE-SPECIFIC was HISTONE H1 KINASE, M PHASE-SPECIFIC 1991-93

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URI

http://www.yso.fi/onto/mesh/D016200

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