Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Biological Factors > Intercellular Signaling Peptides and Proteins > Fibroblast Growth Factors > Fibroblast Growth Factor 2
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Fibroblast Growth Factors > Fibroblast Growth Factor 2
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Fibroblast Growth Factors > Fibroblast Growth Factor 2

Preferred term

Fibroblast Growth Factor 2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Basic Fibroblast Growth Factor
  • Cartilage Derived Growth Factor
  • Cartilage-Derived Growth Factor
  • Class II Heparin-Binding Growth Factor
  • FGF 2
  • FGF-2
  • FGF2
  • Fibroblast Growth Factor-2
  • Fibroblast Growth Factor, Basic
  • HBGF-2
  • Heparin-Binding Growth Factor Class II
  • Prostate Epithelial Cell Growth Factor
  • Prostatropin

Scope note

  • A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).

History note

  • 2001(1991); for FIBROBLAST GROWTH FACTOR-2 use FIBROBLAST GROWTH FACTOR 2 (NM) 1995; for PROSTATROPIN use FIBROBLAST GROWTH FACTOR 2 (NM) 1986-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D016222

Download this concept:

RDF/XML TURTLE JSON-LD Created 6/28/90, last modified 7/9/13