Concept information
Preferred term
Genes, myc
Type
-
Topical Descriptor
Broader concept
Entry terms
- Gene, myc
- myc Gene
- myc Genes
Note
- myc stands for "MYeloCytomatosis"
Scope note
- Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
History note
- 91; was MYC GENES see ONCOGENES 1985-90
In other languages
-
Finnish
-
myc-geeni
-
Swedish
-
c-myc gener
-
c-myc proto-onkogener
-
L-myc gener
-
L-myc proro-onkogener
-
myc onkogener
-
N-myc gener
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N-myc proto-onkogener
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v-myc gener
-
v-myc onkogener
URI
http://www.yso.fi/onto/mesh/D016259
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