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... > Amino Acids, Peptides, and Proteins > Proteins > Viral Proteins > Oncogene Proteins, Viral > Retroviridae Proteins, Oncogenic > Oncogene Protein gp140(v-fms)
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Oncogene Proteins, Viral > Retroviridae Proteins, Oncogenic > Oncogene Protein gp140(v-fms)
... > Amino Acids, Peptides, and Proteins > Proteins > Viral Proteins > Retroviridae Proteins > Retroviridae Proteins, Oncogenic > Oncogene Protein gp140(v-fms)

Preferred term

Oncogene Protein gp140(v-fms)  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • fms Oncogene Product gp140
  • fms Oncogene Protein gp140
  • gp140 v fms
  • gp140 v-fms
  • gp140(v-fms)
  • v-fms, gp140
  • v fms Protein
  • v-fms Protein

Note

  • IM; coord with specific virus (IM); /drug eff /ultrastruct permitted

Scope note

  • Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).

History note

  • 91

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URI

http://www.yso.fi/onto/mesh/D016281

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RDF/XML TURTLE JSON-LD Created 6/19/90, last modified 5/24/19