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... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-abl
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-abl
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Proto-Oncogene Proteins c-abl
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > Proto-Oncogene Proteins c-abl

Preferred term

Proto-Oncogene Proteins c-abl  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • abl Proto Oncogene Products
  • abl Proto-Oncogene Products
  • abl Proto Oncogene Proteins
  • abl Proto-Oncogene Proteins
  • abl, Proto-Oncogene Proteins
  • c abl Proteins
  • c-abl Proteins
  • Products, abl Proto-Oncogene
  • Proteins abl, Proto-Oncogene
  • Proto-Oncogene Products, abl
  • Proto Oncogene Proteins abl
  • Proto-Oncogene Proteins abl
  • Proto-Oncogene Proteins, abl

Scope note

  • Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.

History note

  • 91

In other languages

URI

http://www.yso.fi/onto/mesh/D016315

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