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Concept information

Preferred term

HIV Long Terminal Repeat  

Type

  • Topical Descriptor

Narrower concepts

Entry terms

  • Human Immunodeficiency Virus Long Terminal Repeat
  • Human Immunodeficiency Virus LTR
  • Long Terminal Repeat, HIV
  • LTR, Human Immunodeficiency Virus

Scope note

  • Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.

History note

  • 91

URI

http://www.yso.fi/onto/mesh/D016325

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