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Concept information

Preferred term

Sp1 Transcription Factor  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Specificity Protein 1 Transcription Factor
  • Transcription Factor, Sp1

Note

  • /drug eff /ultrastruct permitted; in titles & translations use SP1 (the figure one), not SPl (the letter l)

Scope note

  • Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.

History note

  • 2006(1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D016329

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