Concept information
Preferred term
Sp1 Transcription Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Specificity Protein 1 Transcription Factor
- Transcription Factor, Sp1
Note
- /drug eff /ultrastruct permitted; in titles & translations use SP1 (the figure one), not SPl (the letter l)
Scope note
- Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.
History note
- 2006(1991)
In other languages
-
Finnish
-
transkriptiotekijä Sp1
-
Swedish
-
Transkriptionsfaktor, Sp1
URI
http://www.yso.fi/onto/mesh/D016329
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